Antihyperglycemic potential of saponin-enriched fraction from Pithecellobium dulce Benth. seed extract

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Antihyperglycemic Potential of Saponin-enriched Fraction from Pithecellobium dulce Benth. Seed Extract

Background Indian traditional system of medicine uses Pithecellobium dulce for the treatment of diabetes mellitus. Objectives This study aims to develop an extract rich in saponins derived from seeds of the plant and to evaluate its antihyperglycemic potential in vitro and in vivo. Materials and Methods Defatted seeds were extracted with methanol and processed to afford saponin-enriched fra...

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Effect of Pithecellobium dulce (Roxb.) Benth. fruit extract on cysteamine induced duodenal ulcer in rats.

The edible fruits of Pithecellobium dulce (Roxb.) Benth. are traditionally used for various gastric complications in India. Here, we investigated the antiulcer activity of hydroalcoholic fruit extract of P. dulce (HAEPD) by applying cysteamine induced duodenal ulcer model in rats. Duodenal ulcer was induced in male albino Wistar rats by oral administration of cysteamine @ 420 mg/kg body wt. as ...

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Nutritional and nutraceutical characteristics of white and red Pithecellobium dulce (Roxb.) Benth fruits

Abstract – Introduction. Pithecellobium dulce is a legume native to tropical America that produces edible arils which can be white or red. The plant is also grown in Asia and, to date, predominantly fruits produced in Asia have been the subject of scientific studies. We studied white and red arils produced in America. Materials and methods. White aril and red aril fruits were evaluated in an ar...

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Ultrastructural Studies on Root Nodules of Pithecellobium dulce (Roxb.) Benth. (Fabaceae)

Ultrastructural studies were conducted on Pithecellobium dulce (Roxb) Benth. root nodules collected from trees growing under natural conditions. Rhizobial infection on root surface of P. dulce started with curling of root hair. Both curled and straight root hairs were observed. Th e internal structure of a mature nodule showed an epidermis, cortex, vascular region and a bacteriod region. Vascul...

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Pharmacological Screening of Pithecellobium dulce benth for its antidiabetic and other potentials

Rao C. A. et al; (2003) evaluated hypoglycemic and antihyperglycemic activity of ethanolic fraction of fruits of Terminalia pallid at different doses in normal and alloxan diabetic rats. The ethanolic extract of fruits of TP at a dose of 0.5 g/kg b.w. could produce a significant fall in blood glucose levels by about 24% in diabetic rats, after 5 h of treatment. But none of these extracts could ...

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ژورنال

عنوان ژورنال: Pharmacognosy Research

سال: 2017

ISSN: 0974-8490

DOI: 10.4103/pr.pr_18_17